Metabolismo do Eritrócito e hemoglobina

Metabolismo do Eritrócito e hemoglobina

(Parte 1 de 6)

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Disco bicôncavo Diâmetro mØdio: 8 micras

ElÆstica

AusŒncia de organelas citoplasmÆticas

Citoplasma rico em Hemoglobina, enzimas, íons, Ægua e glicose pdfMachine

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Aspectos importantes para a manuten Aspectos importantes para a manutençç ªo e ªo e fun funçç ªo:

ªo:

Integridade da membrana Integridade da membrana

Vias metab Vias metabóó licas licas

Estrutura e fun Estrutura e funçç ªo da hemoglobina ªo da hemoglobina pdfMachine

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95% da camada lip 95% da camada lipíí dica contŒm:

dica contŒm:

Colesterol Colesterol

Bicamada Lip Bicamada Lipíí dica (fosfol dica (fosfolíí pides) pides)

Outros 5% Outros 5%

Glicolip Glicolipíí deos deos

Propriedades antigŒnicas da membrana

Propriedades antigŒnicas da membrana

` cidos Graxos livres cidos Graxos livres pdfMachine

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Alteraçªo na composiçªo lipídica pode produzir cØlulas em alvo e acantócitos.

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Integral Integral

Glicoforinas Glicoforinas A,B,C A,B,C

Carregam ant Carregam antíí genos do GV e garantem sua carga genos do GV e garantem sua carga negativa negativa

Band Band 3 3

Sí tio de liga tio de ligaçç ªo do ªo do citoesqueleto citoesqueleto com a membrana com a membrana

Funcionam como prote Funcionam como proteíí nas de sa nas de saíí da de anions da de anions

Perif PerifØØ rica (esqueleto) rica (esqueleto)

Espectrina Espectrina ,

Actina Actina ,

Anquiirina Anquiirina ,

Contribuem para a forma celular e para a estabilidade Contribuem para a forma celular e para a estabilidade da membrana. da membrana.

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Produçªo anormal de espectrina produz esferócitos e eliptócitos.

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(Parte 1 de 6)

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