Limites de radiação não ionizante

Limites de radiação não ionizante

(Parte 4 de 13)

Interpretation of several observed biological effects of AM electromagnetic fields is further complicated by the apparent existence of “windows” of response in both the power density and frequency domains. There are no accepted models that adequately explain this phenomenon, which challenges the traditional concept of a monotonic relationship between the field intensity and the severity of the resulting biological effects.

Overall, the literature on athermal effects of AM electromagnetic fields is so complex, the validity of reported effects so poorly established, and the relevance of the effects to human health is so uncertain, that it is impossible to use this body of information as a basis for setting limits on human exposure to these fields.

Indirect effects of electromagnetic fields

In the frequency range of about 100 kHz–110 MHz, shocks and burns can result either from an individual touching an ungrounded metal object that has acquired a charge in a field or from contact between a charged individual and a grounded metal object. It should be noted that the upper frequency for contact current (110 MHz) is imposed by a lack of data on higher frequencies rather than by the absence of effects. However, 110 MHz is the upper frequency limit of the FM broadcast band. Threshold currents that result in biological effects ranging in severity from perception to pain have been measured in controlled experiments on volunteers (Chatterjee et al. 1986; Tenforde and Kaune 1987; Bernhardt 1988); these are summarized in Table 3. In general, it has been shown that the threshold currents that produce perception and pain vary little over the frequency range 100 kHz–1 MHz and are unlikely to vary significantly over the frequency range up to about 110 MHz. As noted earlier for lower frequencies, significant variations between the sensitivities of men, women, and children also exist for higher frequency fields. The data in Table 3 represent the range of 50th percentile values for people of different sizes and different levels of sensitivity to contact currents.

Summary of biological effects and epidemiological studies (100 kHz–300 GHz)

Available experimental evidence indicates that the exposure of resting humans for approximately 30 min to EMF producing a whole-body SAR of between 1a nd4Wk g21 results in a body temperature increase of less than 1 °C. Animal data indicate a threshold for behavioral responses in the same SAR range. Exposure to more intense fields, producing SAR values in excess of4Wk g21, can overwhelm the thermoregulatory capacity of the body and produce harmful levels of tissue heating. Many laboratory studies with rodent and nonhuman primate models have demonstrated the broad range of tissue damage resulting from either partial-body or whole-body heating producing temperature rises in excess of 1–2°C. The sensitivity of various types of tissue to thermal damage varies widely, but the threshold for irreversible effects in even the most sensitive tissues is greater than4Wk g21 under normal environmental conditions. These data form the basis for an occupational exposure restriction of 0.4 W kg21, which provides a large margin of safety for other limiting conditions such as high ambient temperature, humidity, or level of physical activity.

Both laboratory data and the results of limited human studies (Michaelson and Elson 1996) make it clear that thermally stressful environments and the use of drugs or alcohol can compromise the thermoregulatory capacity of the body. Under these conditions, safety factors should be introduced to provide adequate protection for exposed individuals.

Data on human responses to high-frequency EMF that produce detectable heating have been obtained from controlled exposure of volunteers and from epidemiological studies on workers exposed to sources such as radar, medical diathermy equipment, and heat sealers. They are fully supportive of the conclusions drawn from laboratory work, that adverse biological effects can be caused by temperature rises in tissue that exceed 1°C. Epidemiological studies on exposed workers and the general public have shown no major health effects associated with typical exposure environments. Although there are deficiencies in the epidemiological work, such as poor exposure assessment, the studies have yielded no convincing evidence that typical exposure levels lead to adverse reproductive outcomes or an increased cancer risk in exposed individuals. This is consistent with the results of laboratory research on cellular and animal

Table 3. Ranges of threshold currents for indirect effects, including children, women, and men.

Indirect effect

Threshold current (mA) at frequency:

100 kHz 1 MHz

Touch perception 25–40 25–40 Pain on finger contact 3–5 28–50 Painful shock/let-go threshold 112–224 Not determined Severe shock/breathing difficulty 160–320 Not determined

507Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields ● ICNIRP GUIDELINES models, which have demonstrated neither teratogenic nor carcinogenic effects of exposure to athermal levels of high-frequency EMF.

Exposure to pulsed EMF of sufficient intensity leads to certain predictable effects such as the microwave hearing phenomenon and various behavioral responses. Epidemiological studies on exposed workers and the general public have provided limited information and failed to demonstrate any health effects. Reports of severe retinal damage have been challenged following unsuccessful attempts to replicate the findings.

A large number of studies of the biological effects of amplitude-modulated EMF, mostly conducted with low levels of exposure, have yielded both positive and negative results. Thorough analysis of these studies reveals that the effects of AM fields vary widely with the exposure parameters, the types of cells and tissues involved, and the biological end-points that are examined. In general, the effects of exposure of biological systems to athermal levels of amplitude-modulated EMF are small and very difficult to relate to potential health effects. There is no convincing evidence of frequency and power density windows of response to these fields.

Shocks and burns can be the adverse indirect effects of high-frequency EMF involving human contact with metallic objects in the field. At frequencies of 100 kHz–110 MHz (the upper limit of the FM broadcast band), the threshold levels of contact current that produce effects ranging from perception to severe pain do not vary significantly as a function of the field frequency. The threshold for perception ranges from 25 to 40 mA in individuals of different sizes, and that for pain from approximately 30 to 5 mA; above 50 mA there may be severe burns at the site of tissue contact with a metallic conductor in the field.

Occupational and general public exposure limitations

The occupationally exposed population consists of adults who are generally exposed under known conditions and are trained to be aware of potential risk and to take appropriate precautions. By contrast, the general public comprises individuals of all ages and of varying health status, and may include particularly susceptible groups or individuals. In many cases, members of the public are unaware of their exposure to EMF. Moreover, individual members of the public cannot reasonably be expected to take precautions to minimize or avoid exposure. It is these considerations that underlie the adoption of more stringent exposure restrictions for the public than for the occupationally exposed population.

Basic restrictions and reference levels

Restrictions on the effects of exposure are based on established health effects and are termed basic restrictions. Depending on frequency, the physical quantities used to specify the basic restrictions on exposure to EMF are current density, SAR, and power density. Protection against adverse health effects requires that these basic restrictions are not exceeded.

Reference levels of exposure are provided for comparison with measured values of physical quantities; compliancewith all referencelevels given in these guidelines will ensure compliance with basic restrictions. If measuredvaluesarehigherthanreferencelevels,it doesnot necessarily follow that the basic restrictions have been exceeded,buta moredetailedanalysisis necessaryto assess compliancewith the basic restrictions.

General statement on safety factors

There is insufficient information on the biological and health effects of EMF exposure of human populations and experimental animals to provide a rigorous basis for establishing safety factors over the whole frequency range and for all frequency modulations. In addition, some of the uncertainty regarding the appropriate safety factor derives from a lack of knowledge regarding the appropriate dosimetry (Repacholi 1998). The following general variables were considered in the development of safety factors for high-frequency fields:

● effects of EMF exposure under severe environmental conditions (high temperature, etc.) and/or high activity levels; and c the potentially higher thermal sensitivity in cer- tain population groups, such as the frail and/or elderly, infants and young children, and people with diseases or taking medications that compromise thermal tolerance.

The following additional factors were taken into accountin derivingreferencelevelsfor high-frequencyfields:

c differences in absorption of electromagnetic energy by individuals of different sizes and different orientations relative to the field; and c reflection, focusing, and scattering of the incident field, which can result in enhanced localized absorption of high-frequency energy.

Basic restrictions

Different scientific bases were used in the development of basic exposure restrictions for various frequency ranges:

c Between 1 Hz and 10 MHz, basic restrictions are provided on current density to prevent effects on nervous system functions; c Between 100 kHz and 10 GHz, basic restrictions on SAR are provided to prevent whole-body heat stress and excessive localized tissue heating; in the 100 kHz–10 MHz range, restrictions are provided on both current density and SAR; and c Between 10 and 300 GHz, basic restrictions are provided on power density to prevent excessive heating in tissue at or near the body surface.

508 Health Physics April 1998, Volume 74, Number 4

In the frequency range from a few Hz to 1 kHz, for levels of induced current density above 100 mA m22, the thresholds for acute changes in central nervous system excitability and other acute effects such as reversal of the visually evoked potential are exceeded. In view of the safety considerations above, it was decided that, for frequencies in the range 4 Hz to 1 kHz, occupational exposure should be limited to fields that induce current densities less than 10 mA m22, i.e., to use a safety factor of 10. For the general public an additional factor of 5 is applied, giving a basic exposure restriction of 2 mA m22 .

Below 4 Hz and above 1 kHz, the basic restriction on induced current density increases progressively, corresponding to the increase in the threshold for nerve stimulation for these frequency ranges.

Established biological and health effects in the frequency range from 10 MHz to a few GHz are consistent with responses to a body temperature rise of more than 1°C. This level of temperature increase results from exposure of individuals under moderate environmental conditions to a whole-body SAR of approximately4Wk g21 for about 30 min. A whole-body average SAR of 0.4 W kg21 has therefore been chosen as the restriction that provides adequate protection for occupational exposure. An additional safety factor of 5 is introduced for exposure of the public, giving an average whole-body SAR limit of 0.08 W kg21 .

The lower basic restrictions for exposure of the general public take into account the fact that their age and health status may differ from those of workers.

In the low-frequency range, there are currently few data relating transient currents to health effects. The ICNIRP therefore recommends that the restrictions on current densities induced by transient or very short-term peak fields be regarded as instantaneous values which should not be time-averaged.

The basic restrictions for current densities, wholebody average SAR, and localized SAR for frequencies between 1 Hz and 10 GHz are presented in Table 4, and those for power densities for frequencies of 10–300 GHz are presented in Table 5.

Where appropriate, the reference levels are obtained from the basic restrictions by mathematical modeling and by extrapolation from the results of laboratory investigations at specificfrequencies.They are given for the condition of maximum coupling of the field to the exposed individual,thereby providingmaximum protection.Tables 6 and 7 summarize the reference levels for occupational exposure and exposure of the general public, respectively, and the referencelevelsare illustratedin Figs. 1 and 2. The referencelevelsare intendedto be spatiallyaveragedvalues over the entirebody of the exposedindividual,but with the important proviso that the basic restrictions on localized exposureare not exceeded.

For low-frequency fields, several computational and measurement methods have been developed for deriving field-strength reference levels from the basic restrictions.

Table 4. Basic restrictions for time varying electric and magnetic fields for frequencies up to 10 GHz.a

Exposure characteristics Frequency range

Current density for head and trunk (mA m22) (rms)

Whole-body average SAR (W kg21)

Localized SAR (head and trunk)

Localized SAR (limbs) (W kg21)

a Note: 1. f is the frequency in hertz. 2. Because of electrical inhomogeneity of the body, current densities should be averaged over a cross-section of 1 cm2 perpendicular to the current direction. 3. For frequencies up to 100 kHz, peak current density values can be obtained by multiplying the rms value by u2( ;1.414). For pulses of duration tp the equivalent frequency to apply in the basic restrictions should be calculated as f 5 1/(2 tp). 4. For frequencies up to 100 kHz and for pulsed magnetic fields, the maximum current density associated with the pulses can be calculated from the rise/fall times and the maximum rate of change of magnetic flux density. The induced current density can then be compared with the appropriate basic restriction. 5. All SAR values are to be averaged over any 6-min period. 6. Localized SAR averaging mass is any 10 g of contiguous tissue; the maximum SAR so obtained should be the value used for the estimation of exposure.

7. For pulses of duration tp the equivalent frequency to apply in the basic restrictions should be calculated as f 5 1/(2 tp). Additionally, for pulsed exposures in the frequency range 0.3 to 10 GHz and for localized exposure of the head, in order to limit or avoid auditory effects caused by thermoelastic expansion, an additional basic restriction is recommended. This is that the SA should not exceed 10 mJ kg21 for workers and 2mJ kg21 for the general public, averaged over 10g tissue.

509Guidelines for limiting exposure to time-varying electric, magnetic, and electromagnetic fields c ICNIRP GUIDELINES

The simplificationsthat have been used to date did not account for phenomenasuch as the inhomogeneousdistribution and anisotropy of the electrical conductivity and other tissue factors of importancefor these calculations.

The frequency dependence of the reference field levels is consistent with data on both biological effects and coupling of the field.

(Parte 4 de 13)

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